Vaccination
the act or art of view of protecting it against smallpox, vaccinating; the introduction of vaccine matter into the human frame with the cow and afterward by direct transmisor rendering that disease less formidable. It was at first supposed that the cowpox had arisen by the transmission to the cow of a disease in the horse vaccine lymph is introduced into the first after it had been passed through the cow and afterward by direct transmis- sion. Its employment has long since been abandoned. The cowpox is not pro- duced in the human frame by effluvia; actual inoculation is required. When vaccine lymph is introduced into the arm of an infant, by one or more punc- tures of a lancet, no noticeable effect is and others for vaccinating purposes, at arm of an infant, by one or more puncwhich was largely employed by Jenner tures of a lancet, no noticeable effect is first after it had been passed through the sion. Its employment has long since been abandoned. The cowpox is not produced in the human frame by effluvia; actual inoculation is required. When VACCINE THERAPY discernible for two days. Then a slight papula arises, which, on the 5th or 6th day, becomes of a bluish color and vesicular, with a raised head and a central cup. On the 8th day it reaches full devolopment, and an inflammatory areola appears, which spreads with the extension of the vesicle for two more days. Then a crust or scale is produced in the center of the vesicle, and gradually extends till it covers it in every part. On the 14th or 15th day the scale becomes hard and brown; it next contracts, dries, and blackens, till, between the 20th and the 25th day, it falls off, leaving a permanent circular, depressed, and foveated cicatrix. Unless it possesses all these characters, and specially unless foveation be present, vaccination is imperfect, and cannot be relied on as a prophylactic against smallpox. See VACCINE THERAPY.